HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-Dimethoxybenzaldehyde → 1-(Benzo[b]thiophen-5-ylmethyl)-6-(2,6-dimethoxyphenyl)piperidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-Dimethoxybenzaldehyde | HCID 96404 | — |
| Reactant | 1-Benzothiophen-5-ylmethylamine | HCID 2795448 | — |
| Product | 1-(Benzo[b]thiophen-5-ylmethyl)-6-(2,6-dimethoxyphenyl)piperidin-2-one | HCID 69083767 | — |
Reaction Steps
Prepared according to the described general procedure 6 (GP6) with commercially available benzo[b]thiophen-5-ylmethanamine and commercially available 2,6-dimethoxybenzaldehyde. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions E): tR=0.79 min.; [M+H]+: 382.09 g/mol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09242970B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-d0e2ab34fbf249d09b4d19a726313e3a |
| Source note | uspto-grants-2016_01 |