HuagongsheHuagongshe Chemistry Print Report · For research reference only
9-Methyl-9H-carbazole-3-carbaldehyde → 7-(3,5-dimethoxypyridin-4-yl)-1-((9-methyl-9H-carbazol-3-yl)methyl)azepan-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 9-Methyl-9H-carbazole-3-carbaldehyde | HCID 610666 | — |
| Reactant | Methyl 6-amino-6-(3,5-dimethoxypyridin-4-yl)hexanoate | HCID 69085562 | — |
| Product | 7-(3,5-dimethoxypyridin-4-yl)-1-((9-methyl-9H-carbazol-3-yl)methyl)azepan-2-one | HCID 69084994 | — |
Reaction Steps
Prepared according to the described general procedure 1 (GP1) by reaction of methyl 6-amino-6-(3,5-dimethoxypyridin-4-yl)hexanoate with commercially available 9-methyl-9H-carbazole-3-carbaldehyde. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions A): tR=0.68 min.; [M+H]+: 444.02 g/mol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09242970B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-44bd598706f5402d9ca9be6074e664c0 |
| Source note | uspto-grants-2016_01 |