HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Phenoxythiazole-4-carbaldehyde → 6-(2,6-Dimethoxyphenyl)-1-((2-phenoxythiazol-4-yl)methyl)piperidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Phenoxythiazole-4-carbaldehyde | HCID 13102642 | — |
| Reactant | Methyl 5-amino-5-(2,6-dimethoxyphenyl)pentanoate | HCID 69082713 | — |
| Product | 6-(2,6-Dimethoxyphenyl)-1-((2-phenoxythiazol-4-yl)methyl)piperidin-2-one | HCID 69081326 | — |
Reaction Steps
Prepared according to the described general procedure 1 (GP1) by reaction of methyl 5-amino-5-(2,6-dimethoxyphenyl)pentanoate with 2-phenoxythiazole-4-carbaldehyde. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions A): tR=0.86 min.; [M+H]+: 424.82 g/mol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09242970B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-ebe3c2e9319a4225a1a0bf7fa4d93087 |
| Source note | uspto-grants-2016_01 |