HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Phenylbenzaldehyde → 5-([1,1'-Biphenyl]-2-yl)-1-([1,1'-biphenyl]-3-ylmethyl)-3-methylpyrrolidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Phenylbenzaldehyde | HCID 121053 | — |
| Reactant | Ethyl 4-([1,1'-biphenyl]-2-yl)-4-amino-2-methylbutanoate | HCID 69082640 | — |
| Product | 5-([1,1'-Biphenyl]-2-yl)-1-([1,1'-biphenyl]-3-ylmethyl)-3-methylpyrrolidin-2-one | HCID 69082517 | — |
Reaction Steps
Prepared according to the described general procedure 2 (GP2) by reaction of ethyl 4-([1,1′-biphenyl]-2-yl)-4-amino-2-methylbutanoate with commercially available [1,1′-biphenyl]-3-carbaldehyde. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions A): tR=1.05 min.; [M+H]+: 417.80 g/mol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09242970B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-ac5cae65df2842eaa69ec78487fcd972 |
| Source note | uspto-grants-2016_01 |