HuagongsheHuagongshe Chemistry Print Report · For research reference only
9-Methyl-9H-carbazole-3-carbaldehyde → 5-(2,6-dimethoxyphenyl)-3-methyl-1-((9-methyl-9H-carbazol-3-yl)methyl)pyrrolidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 9-Methyl-9H-carbazole-3-carbaldehyde | HCID 610666 | — |
| Reactant | Ethyl 4-amino-4-(2,6-dimethoxyphenyl)-2-methylbutanoate | HCID 69085588 | — |
| Product | 5-(2,6-dimethoxyphenyl)-3-methyl-1-((9-methyl-9H-carbazol-3-yl)methyl)pyrrolidin-2-one | HCID 69081708 | — |
Reaction Steps
Prepared according to the described general procedure 2 (GP2) by reaction of ethyl 4-amino-4-(2,6-dimethoxyphenyl)-2-methylbutanoate with commercially available 9-methyl-9H-carbazole-3-carbaldehyde. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions A): tR=0.94 min.; [M+H]+: 429.05 g/mol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09242970B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-9532b37c9baa4682877869448633beb4 |
| Source note | uspto-grants-2016_01 |