Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 594755Generated: October 30, 2026

3-Phenoxybenzaldehyde → 6-(2-Methoxynaphthalen-1-yl)-1-(3-phenoxybenzyl)piperidin-2-one

https://huagongshe.com/reaction/594755

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-PhenoxybenzaldehydeHCID 38284—
ReactantMethyl 5-amino-5-(2-methoxynaphthalen-1-yl)pentanoateHCID 69082274—
Product6-(2-Methoxynaphthalen-1-yl)-1-(3-phenoxybenzyl)piperidin-2-oneHCID 69083533—

Reaction Steps

Prepared according to general procedure 1 (GP1) using methyl 5-amino-5-(2-methoxynaphthalen-1-yl)pentanoate and commercially available 3-phenoxybenzaldehyde. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions A): tR=0.99 min.; [M+H]+: 438.14 g/mol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09242970B2
Source datasetuspto-grants-2016_01
ORD IDord-3d55138d970b4e74809bb09139bb3794
Source noteuspto-grants-2016_01