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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 594998Generated: October 31, 2026

HCID 66765592, compound → HCID 66765276, compound

https://huagongshe.com/reaction/594998

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 66765592HCID 66765592—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 66765276HCID 66765276—

Reaction Steps

3-(4-nitro-1H-pyrazol-1-yl)-1-(piperidin-1-yl)propan-1-one (4.4 mmol) was dissolved in 5 mL methanol and palladium on carbon added under an inert atmosphere. The reaction mixture was stirred overnight at rt under hydrogen atmosphere. The resulting mixture was filtered through Celite and the filtrate concentrated in vacuo to give 3-(4-amino-1H-pyrazol-1-yl)-1-(piperidin-1-yl)propan-1-one in a quantitative yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09242987B2
Source datasetuspto-grants-2016_01
ORD IDord-019cf0f2dd684d8789d1c4031650fa60
Source noteuspto-grants-2016_01