HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → N-(5-methyl-7-oxo-4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 2-Amino-5-methyl-4,5,6-trihydrobenzothiazol-7-one | HCID 2756510 | — |
| Product | N-(5-methyl-7-oxo-4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)acetamide | HCID 4644134 | — |
Reaction Steps
A solution of 2-amino-5-methyl-5,6-dihydro-4H-benzothiazol-7-one (25.0 g, 0.137 mol) in Ac2O (300 mL) is heated at reflux temperature for 3 h. The reaction mixture is then cooled to RT and the precipitate is filtered off to afford N-(5-methyl-7-oxo-4,5,6,7-tetrahydro-benzothiazol-2-yl)-acetamide. Yield: 26 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09243000B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-485fbe84d46b4a4aa9db90c4418367ca |
| Source note | uspto-grants-2016_01 |