HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aminoacetaldehyde dimethyl acetal → HCID 178498786, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aminoacetaldehyde dimethyl acetal | HCID 89728 | — |
| Reactant | methyl 7-amino-3-methylsulfanyl-2H-benzo[1,4]oxazine-8-carboxylate | HCID 86712826 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178498786 | HCID 178498786 | 115.1% |
Reaction Steps
A solution of methyl 7-amino-3-methylsulfanyl-2H-benzo[1,4]oxazine-8-carboxylate (Intermediate 28, 0.645 g) and aminoacetaldehyde dimethylacetal (0.403 g) in ethanol (15 mL) was heated to reflux for 4 days. After cooling, the mixture was concentrated in vacuo to give methyl 7-amino-3-(2,2-dimethoxyethylamino)-2H-benzo[1,4]oxazine-8-carboxylate (0.910 g) as a brown oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09242997B2 |
| Source dataset | uspto-grants-2016_01 |
| ORD ID | ord-a6369f03db6b430e8fbf6954f7f4e7f0 |
| Source note | uspto-grants-2016_01 |