N-Lauroyl-L-glutamic acid → lauroylglutamic acid anhydride

Participants

Reaction Steps

100 g of Nα-lauroyl-L-glutamic acid was heated with stirring for 5 hours at 60° C. in 200 g of acetic anhydride, and then cooled to room temperature with stirring to allow a crystal to precipitate. This crystal was washed with 1000 mL of hexane and dried to obtain 72.4 g of Nα-lauroyl-L-glutamic anhydride.

Provenance & Evidence