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HRID596068

反应详情

EQUATION

反应方程式

HRID 596068 的结构方程式

REACTANTS

反应物

2
结构：Cc1c(B2OC(C)(C)C(C)(C)O2)cnn1C
HCID42647313

1,5-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

C11H19BN2O2

结构：COC(=O)c1ccc(-c2cc(Br)cnc2N)cc1F
HCID118045477

未命名化合物

PRODUCTS

生成物

1
结构：Cc1c(-c2cnc(N)c(-c3ccc(C(=O)O)c(F)c3)c2)cnn1C
HCID118045598

未命名化合物

PROCEDURE

实验过程

Following Steps 1 and 2 in Scheme 97, using methyl 4-(2-amino-5-bromopyridin-3-yl)-2-fluorobenzoate and 1,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole, 4-(2-amino-5-(1,5-dimethyl-1H-pyrazol-4-yl)pyridin-3-yl)-2-fluorobenzoic acid was obtained. LCMS (m/z): 327.1 (MH+), 0.45 min.