反应详情

温度

95 °C

A mixture of p-(difluoromethylthio)aniline (4.0 g.), sodium azide (4.0 g.), triethyl orthoformate (25 ml.), and acetic acid (25 ml.) was heated at 95° C. for 4.5 hours and then evaporated at reduced pressure. The residue was diluted with water, filtered, dried and recrystallized from ethyl acetate:hexane to give crystals, m.p. 94°-97° C.

1. customevaporated at reduced pressure
2. additionThe residue was diluted with water
3. filtrationfiltered
4. customdried
5. customrecrystallized from ethyl acetate
6. customhexane to give crystals, m.p. 94°-97° C.