Ethyl orthoformate → HCID 21450973, compound

HRID 596157Notes

Reaction equation

[F:1][CH2:2][S:3][C:4]1[CH:10]=[CH:9][C:7]([NH2:8])=[CH:6][CH:5]=1.[CH2:11](OC(OCC)OCC)C.[N-:21]=[N+:22]=[N-:23].[Na+]>>[F:1][CH2:2][S:3][C:4]1[CH:10]=[CH:9][C:7]([N:8]2[CH:11]=[N:23][N:22]=[N:21]2)=[CH:6][CH:5]=1

Participants

Reactant 3

HCID 31214Ethyl orthoformate

HCID 33557Sodium Azide

HCID 21450968HCID 21450968, compound

Product 1

HCID 21450973HCID 21450973, compound

Procedure

In accordance with the procedure described in Example 1, treatment of p-(fluoromethylthio)aniline with triethylorthoformate and sodium azide furnishes the 1-[p-(fluoromethylthio)phenyl]-1H-tetrazole.

Sources & evidence

ORD record: ord-6cecdfd45f8043ea88e68ff3e0bd653d
Source dataset: uspto-grants-1977_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04010179

Reaction notes

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