Cyclohexene → HEXAHYDROISOXAZOLE,3-(1-METHYL-5-NITROIMIDAZOLYL

HRID 596206Notes

Reaction equation

HRID 596206 reaction equation
[CH:1]1CCCCC=1.[O:7]1[CH:11]2[CH2:12][CH2:13][CH2:14][CH2:15][CH:10]2[C:9]([C:16]2[NH:17][C:18]([N+:21]([O-:23])=[O:22])=[CH:19][N:20]=2)=[N:8]1>>[CH3:1][N:17]1[C:18]([N+:21]([O-:23])=[O:22])=[CH:19][N:20]=[C:16]1[C:9]1[CH:10]2[CH2:15][CH2:14][CH2:13][CH2:12][CH:11]2[O:7][N:8]=1

Participants

3

Reactant 2

HCID 8079CyclohexeneHCID 136354663HCID 136354663, compound

Product 1

HCID 119263HEXAHYDROISOXAZOLE,3-(1-METHYL-5-NITROIMIDAZOLYL

Procedure

Following the same procedure as in Example 30, the hydroxamoylchloride prepared as in Example 7 is reacted with cyclohexene. The product, 2-(3a,4,5,6,7,7a-hexahydro-1,2-benz-isoxazol-3-yl)-5-nitroimidazole has a melting point of 119°-121° C.

Workup

  1. customthe hydroxamoylchloride prepared as in Example 7

Sources & evidence

ORD record
ord-15a223de967d43408beaa2c8edb36093
Source dataset
uspto-grants-1977_03
Patent number
US04010176

Reaction notes

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