HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Iodide → N-2-ethyl-cyclohexylamino-3,4,5-trimethoxy-benzoate-hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Iodide | HCID 5238 | — |
| Reactant | N-(2-chloroethyl)cyclohexanamine hydrochloride | HCID 13756691 | — |
| Reactant | Sodium 3,4,5-trimethoxy-benzoate | HCID 86734526 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-2-ethyl-cyclohexylamino-3,4,5-trimethoxy-benzoate-hydrochloride | HCID 88821243 | — |
Reaction Steps
To 1.7 g. of sodium-3,4,5-trimethoxy-benzoate 1.45 g. of N-2-chloroethyl-cyclohexylamine hydrochloride and some sodium iodide crystals are added, whereafter 30 ml. of dimethyl formamide are introduced. After cooling toe precipitated crystals are filtered and the filtrate is evaporated. The residue is recrystallized from 96% of ethanol under clarifying with activated charcoal. Thus N-2-ethyl-cyclohexylamino-3,4,5-trimethoxy-benzoate-hydrochloride is obtained. M.p.: 208°-210° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04010193 |
| Source dataset | uspto-grants-1977_03 |
| ORD ID | ord-eaf5569218344429b65035dc5a7984e5 |
| Source note | uspto-grants-1977_03 |