1-Butanol → HCID 13811056, compound

HRID 596269Notes

Reaction equation

HRID 596269 reaction equation
ClCCC[O:5][P:6]1[CH2:10][CH:9]=[C:8]([CH3:11])[CH2:7]1.Cl[CH2:13][CH:14](Cl)[CH2:15][CH3:16].C(O)CCC>>[CH2:13]([P:6]1(=[O:5])[CH2:10][CH:9]=[C:8]([CH3:11])[CH2:7]1)[CH2:14][CH2:15][CH3:16]

Participants

4

Reactant 3

HCID 2631-ButanolHCID 120171,2-DichlorobutaneHCID 21451191HCID 21451191, compound

Product 1

HCID 13811056HCID 13811056, compoundYield 65.3%

Procedure

To a solution of 26.4 g. (0.137 mole) of 1-(chloropropoxy)-3-methyl-3-phospholene in 57 ml. of 1,2-dichlorobutane was added 30.4 g. (0.411 mole) of n-butanol. The mixture was heated under reflux for 4 hours and then the solvent was removed by evaporation. The residue was distilled under reduced pressure to obtain 15.4 g. (65.3% yield) of 1-butyl-3-methyl-3-phospholene-1-oxide in the form of a liquid having a boiling point of 106° - 116° C at 0.2 mm. of mercury.

Workup

  1. temperatureThe mixture was heated
  2. temperatureunder reflux for 4 hours
  3. customthe solvent was removed by evaporation
  4. distillationThe residue was distilled under reduced pressure
  5. customto obtain 15.4 g

Sources & evidence

ORD record
ord-14abdeec89fe46ac8d7a1fe559669ecc
Source dataset
uspto-grants-1977_03
Patent number
US04010209

Reaction notes

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