Sodium borohydride → HCID 12251398, compound

HRID 596281Notes

Reaction equation

HRID 596281 reaction equation
[CH2:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][C:2]21[CH2:14][CH2:13][C:12](=[O:15])[CH2:11][CH2:10]2.[BH4-].[Na+]>C(O)C>[CH2:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][C:2]21[CH2:10][CH2:11][CH:12]([OH:15])[CH2:13][CH2:14]2

Participants

4

Reactant 2

HCID 4311764Sodium borohydrideHCID 12251437HCID 12251437, compound

Product 1

HCID 12251398HCID 12251398, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

11'. A spiro(cyclohexane-1,2'-indan)-4-one [11] obtained in step (10) has its 4-keto function reduced, e.g., by mixing said compound in ethanol with sodium borohydride at moderate (room) temperature for from about 3 to about 8 hours, to produce a corresponding spiro(cyclohexane-1,2'-indan)-4-ol [14].

Workup

  1. additione.g., by mixing
  2. customfor from about 3 to about 8 hours

Sources & evidence

ORD record
ord-831cdf31c9ed4fa180ecf8229c8b9829
Source dataset
uspto-grants-1977_03
Patent number
US04010201

Reaction notes

Loading…