反应详情

34 g (~0.1 mol) of 3-nitro-4-phenoxy-5-sulphamylbenzoic acid are dissolved in 150 ml of methanol and are heated to the boil. 5.4 ml of concentrated H2SO4 are then added slowly dropwise and the mixture is heated at reflux temperature for 10 hours. On cooling, 3-nitro-4-phenoxy-5-sulphamylbenzoic acid methyl ester crystallises.

1. temperatureare heated to the boil
2. temperaturethe mixture is heated
3. temperatureat reflux temperature for 10 hours
4. temperatureOn cooling
5. custom3-nitro-4-phenoxy-5-sulphamylbenzoic acid methyl ester crystallises