2,4-Dimethoxybenzoyl chloride → HCID 21451923, compound

HRID 596322Notes

Reaction equation

HRID 596322 reaction equation
[NH2:1][CH2:2][CH2:3][C:4]1[CH:9]=[CH:8][C:7]([C:10]2[CH:15]=[CH:14][C:13]([OH:16])=[CH:12][CH:11]=2)=[CH:6][CH:5]=1.[CH3:17][O:18][C:19]1[CH:27]=[C:26]([O:28][CH3:29])[CH:25]=[CH:24][C:20]=1[C:21](Cl)=[O:22]>>[CH3:17][O:18][C:19]1[CH:27]=[C:26]([O:28][CH3:29])[CH:25]=[CH:24][C:20]=1[C:21]([NH:1][CH2:2][CH2:3][C:4]1[CH:9]=[CH:8][C:7]([C:10]2[CH:15]=[CH:14][C:13]([OH:16])=[CH:12][CH:11]=2)=[CH:6][CH:5]=1)=[O:22]

Participants

3

Reactant 2

HCID 27347192,4-Dimethoxybenzoyl chlorideHCID 14850211HCID 14850211, compound

Product 1

HCID 21451923HCID 21451923, compoundYield 80%

Procedure

4-[2-(2,4-Dimethoxy-benzamido)-ethyl]-4'-hydroxy-biphenyl was prepared analogous to Example I from 4-[2-amino-ethyl]-4'-hydroxy-biphenyl and 2,4-dimethoxybenzoyl chloride.

Sources & evidence

ORD record
ord-1fdbffe1b43847e5ad6afe78337f3fa5
Source dataset
uspto-grants-1977_03
Patent number
US04010279

Reaction notes

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