HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Iodide → HCID 23328739, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Iodide | HCID 4875 | — |
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | 8-chloro-1-(chloromethyl)-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine | HCID 12612345 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 23328739 | HCID 23328739 | — |
Reaction Steps
In the manner given in Preparation 48, 8-chloro-1-(chloromethyl)-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine, potassium iodide, and piperidine in tetrahydrofuran are reacted to give 8-chloro-1-(piperidinomethyl)-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04010177 |
| Source dataset | uspto-grants-1977_03 |
| ORD ID | ord-f396c3cad27d44feab2775d657e50962 |
| Source note | uspto-grants-1977_03 |