2-(Phenylacetyl)-1H-isoindole-1,3(2H)-dione → HCID 178524908, compound

HRID 596436Notes

Reaction equation

HRID 596436 reaction equation
[O:1]=[C:2]1C2C=CC=CC=2C2N=C(O)C=[C:5]3[CH:17]=[CH:18][CH:19]=[C:3]1[C:4]=23.C1(C[C:27]([N:29]2[C:33](=[O:34])[C:32]3=[CH:35][CH:36]=[CH:37][CH:38]=[C:31]3[C:30]2=O)=[O:28])C=CC=CC=1>>[OH:28][C:27]1[N:29]=[C:33]([O:34][C:2](=[O:1])[C:3]2[CH:4]=[CH:5][CH:17]=[CH:18][CH:19]=2)[C:32]2[C:31]([CH:30]=1)=[CH:38][CH:37]=[CH:36][CH:35]=2

Participants

3

Reactant 2

HCID 214498962-(Phenylacetyl)-1H-isoindole-1,3(2H)-dioneHCID 178514941HCID 178514941, compound

Product 1

HCID 178524908HCID 178524908, compound

Procedure

7-OXO-7H-dibenzo-[d e,h]-quinolin-2-ol which is useful as an intermediate in the preparation of dyestuffs is prepared by cycloisomerizing the novel compound, N-phenylacetyl phthalimide in an inert solvent and in the presence of a Friedel-Crafts catalyst to form the novel compound O-(3-hydroxy-1-isoquinolinyl)-benzoic acid which is then cyclized by dehydrating condensation to form the 7-oxo-7H-dibenzo-[d e,h]-quinolin-2-ol.

Workup

  1. customis prepared

Sources & evidence

ORD record
ord-dd3cc514b65542eeaa3a8b81eb92db77
Source dataset
uspto-grants-1977_03
Patent number
US04011227

Reaction notes

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