HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 596530Generated: October 27, 2026
Sulfolane → 2-ethyl-10,11-dihydro-5H-dibenzo [a,d]cyclohepten-5-one
https://huagongshe.com/reaction/596530
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sulfolane | HCID 31347 | — |
| Reactant | 2-[2-(3-Methylphenyl)ethyl]benzoic acid | HCID 12398816 | — |
| Reactant | 2-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-one | HCID 12398817 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-ethyl-10,11-dihydro-5H-dibenzo [a,d]cyclohepten-5-one | HCID 22117289 | — |
| Product | 3-(o-Carboxyphenethyl)ethylbenzene | HCID 70638813 | — |
Reaction Steps
75 Gm. of 3-(o-carboxyphenethyl)toluene is dissolved in 400 ml. sulpholane and heated to 110°-120° C. 200 Ml. of polyphosphoric acid is added and the mixture is stirred at 100° C. for 90 minutes, and then poured onto ice and water. The mixture is extracted with hexane and the solution dried and evaporated to give 64 gm., 89%, of 2-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-one as an oil. Use of 3-(o-carboxyphenethyl)ethylbenzene gives a similar yield of 2-ethyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04011243 |
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| Source dataset | uspto-grants-1977_03 |
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| ORD ID | ord-3abb8f04c859485bb5026c13332fec81 |
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| Source note | uspto-grants-1977_03 |
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