5H-Dibenzo(a,d)cycloheptene-2-acetic acid, alpha-methyl-5-oxo- → 5-oxo-5H-dibenzo[a,d]cyclohepten-2-acetic acid

HRID 596536Notes

Reaction equation

HRID 596536 reaction equation
C1COC2(C3C=CC(C(C)CO)=CC=3C=CC3C=CC=CC2=3)O1.[CH:24]1[C:34]2[CH:33]=[CH:32][C:31]3[CH:35]=[CH:36][CH:37]=[CH:38][C:30]=3[C:29](=[O:39])[C:28]=2[CH:27]=[CH:26][C:25]=1[CH:40](C)[C:41]([OH:43])=[O:42].C1COC2(C3C=CC(CCO)=CC=3C=CC3C=CC=CC2=3)O1>>[CH:24]1[C:34]2[CH:33]=[CH:32][C:31]3[CH:35]=[CH:36][CH:37]=[CH:38][C:30]=3[C:29](=[O:39])[C:28]=2[CH:27]=[CH:26][C:25]=1[CH2:40][C:41]([OH:43])=[O:42]

Participants

4

Reactant 3

HCID 1739105H-Dibenzo(a,d)cycloheptene-2-acetic acid, alpha-methyl-5-oxo-HCID 214500012-(5,5-ethylenedioxy-5H-dibenzo[a,d]cyclohepten-2-yl)propan-1-olHCID 214500092-(5,5-ethylenedioxy-5H-dibenzo[a,d]cyclohepten-2-yl)ethanol

Product 1

HCID 123988215-oxo-5H-dibenzo[a,d]cyclohepten-2-acetic acid

Procedure

Using the conditions described in Example 1, 2-(5,5-ethylenedioxy-5H-dibenzo[a,d]cyclohepten-2-yl)propan-1-ol is converted, in similar yield, to 2-(5H-dibenzo[a,d]cyclohepten-5-on-2-yl)propionic acid and 2-(5,5-ethylenedioxy-5H-dibenzo[a,d]cyclohepten-2-yl)ethanol is converted in similar yield to 2-(5H-dibenzo[a,d]cyclohepten-5-on-2-yl)acetic acid.

Sources & evidence

ORD record
ord-7b2c0f60120f4efc99909c8e87281b6e
Source dataset
uspto-grants-1977_03
Patent number
US04011243

Reaction notes

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