HCID 13178927, compound → HCID 13178929, compound

Participants

Reaction Steps

1α,2α-Dihydroxy-3β-acetoxy-cholesta-5-ene (264 mg) was dissolved in a mixture of acetic anhydride (20 ml) and pyridine (2 ml) and the solution was heated on a boiling water bath for 2 hours to remove acetic anhydride. To the solution was added ice-water and the precipitated crystals were recovered by filtration. Recrystallization of the crystals from methanol yielded 1α,2α,3β-triacetoxycholesta-5-ene (230 mg) having a melting point between 109 and 110° C.

Provenance & Evidence