HuagongsheHuagongshe Chemistry Print Report · For research reference only
Styrene Oxide → HCID 10662045, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Styrene Oxide | HCID 7276 | — |
| Reactant | Homoveratrylamine | HCID 8421 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 10662045 | HCID 10662045 | — |
Reaction Steps
A mixture of 100 g. (0.55 mol) of 3,4-dimethoxyphenylethylamine and 66.2 g. (0.55 mol) of styrene oxide in 200 ml. of tetrahydrofuran is refluxed overnight. The solvent is removed in vacuo, about 500 ml. of n-butyl chloride is added and the mixture cooled slightly. Filtration furnishes N-[2-(3,4-dimethoxyphenyl)ethyl]-2-phenyl-2-hydroxyethylamine, m.p. 92°-93° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04011319 |
| Source dataset | uspto-grants-1977_03 |
| ORD ID | ord-b95514401995467184049839ff0bc30b |
| Source note | uspto-grants-1977_03 |