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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 596699Generated: October 30, 2026

Potassium Cyanide → 3-(4-Cyano-3-nitrobenzoyl)propionic acid

https://huagongshe.com/reaction/596699

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CyanideHCID 9032—
Reactant3-(4-Amino-3-nitrobenzoyl)propionic acidHCID 21432170—
ReactantSodium NitriteHCID 23668193—
SolventHydrochloric AcidHCID 313—
Product3-(4-Cyano-3-nitrobenzoyl)propionic acidHCID 21450224—

Reaction Steps

i. 3-(4-Amino-3-nitrobenzoyl)propionic acid was diazotised in aqueous hydrochloric acid with sodium nitrite and the resultant solution treated with cuprous cyanide in potassium cyanide solution to give 3-(4-cyano-3-nitrobenzoyl)propionic acid, also available by a cyanide displacement reaction of 3-(4-fluoro-3-nitrobenzoyl)propionic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04011321
Source datasetuspto-grants-1977_03
ORD IDord-17800858b5c045cc80ee7198d1908575
Source noteuspto-grants-1977_03