1-Diethylamino ethyl-2-phenyl-3-keto piperazine → 1-Diethylamino ethyl-3-phenyl piperazine

HRID 596855Notes

Reaction equation

HRID 596855 reaction equation
[CH2:1]([N:3]([CH2:19][CH3:20])[CH:4]([N:6]1[CH2:11][CH2:10][NH:9][CH:8]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[C:7]1=O)[CH3:5])[CH3:2].C(N(CC)C(N1CCNC(=O)C1C1C=CC=CC=1)C)C>>[CH2:19]([N:3]([CH2:1][CH3:2])[CH:4]([N:6]1[CH2:11][CH2:10][NH:9][CH:8]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH2:7]1)[CH3:5])[CH3:20]

Participants

3

Reactant 2

HCID 214485351-Diethylamino ethyl-2-phenyl-3-keto piperazine2×HCID 215608121-Diethylamino ethyl-2-keto-3-phenyl piperazine2×

Product 1

HCID 706383621-Diethylamino ethyl-3-phenyl piperazine

Procedure

1-Diethylamino ethyl-2-keto-3-phenyl piperazine prepared according to Example 1 B (a) of application Ser. No. 333,497, is reduced by following the procedure described hereinabove in Example 7 (a) whereby, in place of 1-diethylamino ethyl-3-keto-2-phenyl piperazine, the equimolecular amount of said 1-diethylamino ethyl-2-keto-3-phenyl piperazine is reduced. The resulting 3-phenyl piperazine compound is obtained in the form of a light yellow oil boiling at 102° C./0.02 mm. Hg.

Sources & evidence

ORD record
ord-7a4569befdd74837829fdf4a9330867e
Source dataset
uspto-grants-1977_03
Patent number
US04012389

Reaction notes

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