Diethylaminoethyl chloride → HCID 86733024, compound

HRID 596860Notes

Reaction equation

HRID 596860 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:18]=[CH:19][C:20]=1[Cl:21])[CH2:5][N:6]1[CH2:11][CH2:10][NH:9][CH2:8][CH:7]1[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1.C(N(CCCl)CC)C.[O:30]1[CH2:35][CH2:34][N:33]([CH2:36][CH2:37]Cl)[CH2:32][CH2:31]1>>[Cl:1][C:2]1[CH:3]=[C:4]([CH:18]=[CH:19][C:20]=1[Cl:21])[CH2:5][N:6]1[CH2:11][CH2:10][N:9]([CH2:37][CH2:36][N:33]2[CH2:34][CH2:35][O:30][CH2:31][CH2:32]2)[CH2:8][CH:7]1[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1

Participants

4

Reactant 3

HCID 13364Diethylaminoethyl chlorideHCID 767274-(2-Chloroethyl)morpholineHCID 21448557HCID 21448557, compound

Product 1

HCID 86733024HCID 86733024, compound

Procedure

1-(3',4'-Dichloro benzyl)-2-phenyl piperazine prepared according to Example 3 (b), is akylated by following the procedure described in Example 3 (c) whereby, in place of diethylamino ethylchloride, the equimolecular amount of morpholino ethylchloride is used. The resulting reaction product is obtained in the form of a light yellow oil boiling at 230° C./0.04 mm. Hg.

Workup

  1. customThe resulting reaction product

Sources & evidence

ORD record
ord-832fffae8a3642d687013ed89a7129d7
Source dataset
uspto-grants-1977_03
Patent number
US04012389

Reaction notes

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