Diethylaminoethyl chloride → 1-(3',4',5'-Trimethoxy benzyl)-2-phenyl-4-diethylamino ethyl piperazine

HRID 596863Notes

Reaction equation

HRID 596863 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:19]=[C:20]([O:24][CH3:25])[C:21]=1[O:22][CH3:23])[CH2:6][N:7]1[CH2:12][CH2:11][NH:10][CH2:9][CH:8]1[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1.[CH2:26]([N:28]([CH2:31][CH2:32]Cl)[CH2:29][CH3:30])[CH3:27]>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:19]=[C:20]([O:24][CH3:25])[C:21]=1[O:22][CH3:23])[CH2:6][N:7]1[CH2:12][CH2:11][N:10]([CH2:27][CH2:26][N:28]([CH2:31][CH3:32])[CH2:29][CH3:30])[CH2:9][CH:8]1[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

3

Reactant 2

HCID 13364Diethylaminoethyl chlorideHCID 214485551-(3',4',5'-Trimethoxy benzyl)-2-phenyl piperazine

Product 1

HCID 867330251-(3',4',5'-Trimethoxy benzyl)-2-phenyl-4-diethylamino ethyl piperazine

Procedure

1-(3',4',5'-Trimethoxy benzyl)-2-phenyl piperazine prepared according to Example 11, is alkylated by means of diethylamino ethylchloride by following the procedure described in Example 2 (c). The resulting reaction product is obtained in the form of yellow oil boiling at 200° C./0.03 mm. Hg.

Workup

  1. customThe resulting reaction product

Sources & evidence

ORD record
ord-6656cb39b37048388957ee899cdbd2ee
Source dataset
uspto-grants-1977_03
Patent number
US04012389

Reaction notes

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