HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium → 1,3-Dioxo-2,3-dihydro-1H-indene-2-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium | HCID 5360545 | — |
| Reactant | HCID 54508334 | HCID 54508334 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 1,3-Dioxo-2,3-dihydro-1H-indene-2-carbonitrile | HCID 294520 | — |
Reaction Steps
3-Cyanomethylene phthalide (6.0 g.; 0.035 mole) was added to a solution of sodium (0.8 g.) in methanol (35 ml) and the red solution refluxed for 20 mins. On cooling and acidification with one-third of its bulk of concentrated hydrochloric acid the indandione separated as a copious yellow solid, m.p. 204°-207° C (d) (lit. m.p. 201°-202° C).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04012407 |
| Source dataset | uspto-grants-1977_03 |
| ORD ID | ord-3ef5616c28b9452fb2e038713ee4e1d0 |
| Source note | uspto-grants-1977_03 |