Sulfuric Acid → 6,7-Diethyl-3,4-dihydronaphthalen-1(2H)-one

HRID 596895Notes

Reaction equation

HRID 596895 reaction equation
[CH2:1]([C:3]1[CH:4]=[C:5]([CH2:11][CH2:12][CH2:13][C:14]([OH:16])=O)[CH:6]=[CH:7][C:8]=1[CH2:9][CH3:10])[CH3:2].S(=O)(=O)(O)O>>[CH2:1]([C:3]1[CH:4]=[C:5]2[C:6](=[CH:7][C:8]=1[CH2:9][CH3:10])[C:14](=[O:16])[CH2:13][CH2:12][CH2:11]2)[CH3:2]

Participants

3

Reactant 2

HCID 1118Sulfuric AcidHCID 123663984-(3,4-Diethylphenyl)butanoic acid

Product 1

HCID 123663996,7-Diethyl-3,4-dihydronaphthalen-1(2H)-one

Procedure

Alternatively 4-(3',4'-diethylphenyl) butanoic acid (23.3 g; 0.106 mole) maybe cyclised by stirring at 100° C with 80% sulphuric acid (115 ml) for 11/2 hours. After dilution, extraction into ether, and distillation 15.83 g (74%) of the tetralone was obtained.

Workup

  1. extractionAfter dilution, extraction into ether
  2. distillationdistillation 15.83 g (74%) of the tetralone
  3. customwas obtained

Sources & evidence

ORD record
ord-dbd0ba54b1794dcaa7bbb5bbacc5d54c
Source dataset
uspto-grants-1977_03
Patent number
US04012407

Reaction notes

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