HCID 178524272, compound → HCID 178514934, compound

HRID 596972Notes

Reaction equation

HRID 596972 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][C:9]2[CH:17]=[C:16]([C:18]3[NH:22][N:21]=[N:20][N:19]=3)[CH:15]=[CH:14][C:10]=2[C:11](O)=[O:12])=[CH:4][CH:3]=1>[Zn].O>[Cl:1][C:2]1[CH:3]=[C:4]2[C:5]([S:8][C:9]3[CH:17]=[C:16]([C:18]4[NH:22][N:21]=[N:20][N:19]=4)[CH:15]=[CH:14][C:10]=3[C:11]2=[O:12])=[CH:6][CH:7]=1

Participants

4

Reactant 1

HCID 178524272HCID 178524272, compound

Product 1

HCID 178514934HCID 178514934, compound

Reagents, catalysts & solvents 2

HCID 23994ZincCatalystHCID 962WaterSolvent

Procedure

2-(p-Chlorophenylthio)-4-(5-tetrazolyl)benzoic acid (3.41g) was heated with polyphosphoric acid (70g) on a steam bath for 1 hr. The reaction mixture was decomposed by warming with water, and the product filtered off, washed with water, recrystallised from dimethylformamide, and dried at 156° C. in vacuo, giving 7-chloro-3-(5-tetrazolyl)thioxanthone, decomposes without melting.

Workup

  1. filtrationthe product filtered off
  2. washwashed with water
  3. customrecrystallised from dimethylformamide
  4. customdried at 156° C. in vacuo

Sources & evidence

ORD record
ord-50b0c9fbd0434622af37cc72803fab55
Source dataset
uspto-grants-1977_03
Patent number
US04012499

Reaction notes

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