Sulfuric Acid → HCID 70634285, compound

Participants

Reaction Steps

6.5 g. of 3β,20-diacetoxy-15α,16α-methylene-5,17(20)-pregnadien-21-al is mixed in 65 ml. of tetrahydrofuran with 6.5 g. of lithium tri-tert.-butoxyalanate and agitated for 30 minutes at room temperature. The mixture is then stirred into ice water, acidified with dilute sulfuric acid, and extracted with methylene chloride. After drying and evaporation, 6.5 g. of crude 21-hydroxy-3β,20-diacetoxy-15α,16α-methylene-5,17(20)-pregnadiene is obtained.

Provenance & Evidence