Ethyl bromoacetate → HCID 21449484, compound

Participants

Reaction Steps

(1-Hydroxy-2-cyclopentyl-2,6-dimethyl-7-chloro-5-indanyloxy)acetic acid is prepared following substantially the same procedure described in Example 4, Step F, using the following substances: 2-cyclopentyl-2,6-dimethyl-7-chloroindan-1,5-diol (4.2 g., 0.015 mole); potassium carbonate (3.6 g.); ethyl bromoacetate (3.1 ml.); and dimethylformamide (35 ml.), and hydrolyzing the resultant ester with aqueous sodium hydroxide in accordance with Example 4, Step F, there is obtained (1-hydroxy-2-cyclopentyl-2,6-dimethyl-7-chloro-5-indanyloxy)acetic acid.

Provenance & Evidence