2,3-Dichlorothioanisole → 2',3'-Dichloro-4'-methylthio-2-cyclopentylacetophenone

HRID 597022Notes

Reaction equation

HRID 597022 reaction equation
[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][CH:5]=[CH:4][C:3]=1[S:9][CH3:10].[CH:11]1([CH2:16][C:17](Cl)=[O:18])[CH2:15][CH2:14][CH2:13][CH2:12]1.[Cl-].[Al+3].[Cl-].[Cl-]>C(Cl)Cl>[Cl:8][C:7]1[C:2]([Cl:1])=[C:3]([S:9][CH3:10])[CH:4]=[CH:5][C:6]=1[C:17](=[O:18])[CH2:16][CH:11]1[CH2:15][CH2:14][CH2:13][CH2:12]1

Participants

5

Reactant 3

HCID 27582242,3-DichlorothioanisoleHCID 3485182Cyclopentylacetyl chlorideHCID 6451240Aluminum(III) Chloride

Product 1

HCID 203584462',3'-Dichloro-4'-methylthio-2-cyclopentylacetophenone

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

2',3'-Dichloro-4'-methylthio-2-cyclopentylacetophenone is prepared following substantially the same procedure described in Example 3, Step A, using the following substances: 2,3-dichlorothioanisole (63.1 g., 0.327 mole), methylene chloride (300 ml.), cyclopentylacetyl chloride (52.7 g., 0.367 mole) and aluminum chloride (48.0 g., 0.36 mole).

Sources & evidence

ORD record
ord-2db9715d379746e78417b853bc30eb3e
Source dataset
uspto-grants-1977_03
Patent number
US04012524

Reaction notes

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