Dimethylformamide → (Cyclohex-1-en-1-yl)(2,3-dichloro-4-methoxyphenyl)methanone

Participants

Reaction Steps

1-Bromocyclohexyl 2,3-dichloro-4-methoxyphenyl ketone (47.3 g., 0.13 mole), lithium chloride (16.5 g., 0.39 mole) and dimethylformamide (200 ml.) are heated at 90° C for 2 hours, then poured into water (1 l.) to give 36.5 g. of 1-cyclohexenyl 2,3-dichloro-4-methoxyphenyl ketone which melts at 126°-129° C. after drying at 60° C. under vacuum for 16 hours.

Provenance & Evidence