Potassium borohydride → HCID 21449497, compound

HRID 597032Notes

Reaction equation

HRID 597032 reaction equation
[O:1]=[C:2]1[C:10]2[C:5](=[CH:6][C:7]([O:13][CH2:14][C:15]([OH:17])=[O:16])=[C:8]([Cl:12])[C:9]=2[Cl:11])[CH:4]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH:3]1[CH2:24][CH3:25].[BH4-].[K+]>O>[OH:1][CH:2]1[C:10]2[C:5](=[CH:6][C:7]([O:13][CH2:14][C:15]([OH:17])=[O:16])=[C:8]([Cl:12])[C:9]=2[Cl:11])[CH:4]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH:3]1[CH2:24][CH3:25]

Participants

4

Reactant 2

HCID 4192641Potassium borohydrideHCID 12395614HCID 12395614, compound

Product 1

HCID 21449497HCID 21449497, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

(1-Hydroxy-2-ethyl-3-phenyl-6,7-dichloro-5-indanyloxy)acetic acid is prepared following substantially the same procedure described in Example 1, using the following substances: (1-oxo-2-ethyl-3-phenyl-6,7-dichloro-5-indanyloxy)acetic acid (7.58 g., 0.02 mole); potassium borohydride (2.0 g.); and water (200 ml.). Follwing this procedure, there is obtained (1-hydroxy-2-ethyl-3-phenyl-6,7-dichloro-5-indanyloxy)acetic acid.

Workup

  1. custom(1-Hydroxy-2-ethyl-3-phenyl-6,7-dichloro-5-indanyloxy)acetic acid is prepared

Sources & evidence

ORD record
ord-6aa35ba1afca4dd985fb9222fecce566
Source dataset
uspto-grants-1977_03
Patent number
US04012524

Reaction notes

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