Pyridinium chloride → 6,7-Dichloro-5-hydroxy-2-methyl-2-phenylindan-1-one

Participants

Reaction Conditions

Reaction Steps

2-Phenyl-2-methyl-5-methoxy-6,7-dichloro-1-indanone (4.94 g., 0.015 mole) is mixed with pyridine hydrochloride (50 g.) and the mixture is heated at 175° C. for 1 hour, then poured into water (500 ml.) and the product is collected and crystallized from ethanol:water, 2:1 to obtain 2-phenyl-2-methyl-5-hydroxy-6,7-dichloro-1-indanone, m.p. 194°-6° C.

Provenance & Evidence