HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetaldehyde → Desmethyltriazolam
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetaldehyde | HCID 177 | — |
| Reactant | Sodium cyanoborohydride | HCID 5003444 | — |
| Reactant | HCID 21449000 | HCID 21449000 | — |
| Product | Desmethyltriazolam | HCID 826660 | — |
Reaction Steps
In the manner given in Example 22, 1-[2-(methylamino)-propyl]-8-chloro-6-(o-chlorophenyl)-4H-s-triazolo[4,3-a]-[1,4]benzodiazepine is treated successively with acetaldehyde and sodium cyanoborohydride to give 1-[2-N-ethyl-N-methylamino)propyl]-8-chloro-6-(o-chlorophenyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04012413 |
| Source dataset | uspto-grants-1977_03 |
| ORD ID | ord-6554a2a5adf64f16b657c1b2df0bc7b0 |
| Source note | uspto-grants-1977_03 |