Methanol → HCID 178441961, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 2,2-dibromo-3,3-dimethylbutyric acid, 55 parts, and thiocarbohydrazide, 22 parts, in 500 parts of (1:1) methanol and water was heated to reflux for five hours. Upon cooling the reaction mixture to 0° C., a solid formed and was collected. The solid, 4-amino-6-t-butyl-3-mercapto-1,2,4-triazin-5-one, was obtained in 78% of theory (29 parts).

Provenance & Evidence