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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 597149Generated: October 30, 2026

2-Amino-6-(4-methylpiperazin-1-yl)benzonitrile → 1-benzyl-N-[2-cyano-3-(4-methyl-1-piperazinyl)phenyl]-1H-tetrazole-5-carboxamide

https://huagongshe.com/reaction/597149

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-6-(4-methylpiperazin-1-yl)benzonitrileHCID 12715726—
Reactant1-benzyl-1H-tetrazole-5-carbonyl chlorideHCID 20463876—
Product1-benzyl-N-[2-cyano-3-(4-methyl-1-piperazinyl)phenyl]-1H-tetrazole-5-carboxamideHCID 22756811—

Reaction Steps

In a manner similar to Example I, 1-benzyl-1H-tetrazole-5-carbonyl chloride is condensed with 2-amino-6-(4-methyl-1-piperazinyl)benzonitrile to give 1-benzyl-N-[2-cyano-3-(4-methyl-1-piperazinyl)phenyl]-1H-tetrazole-5-carboxamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04013647
Source datasetuspto-grants-1977_03
ORD IDord-76262225064c49de982b33a34d884ea4
Source noteuspto-grants-1977_03