Dimethylamine → HCID 70632488, compound

HRID 597165Notes

Reaction equation

HRID 597165 reaction equation
[C:1]1([CH2:7][C:8]([NH:10][CH:11]2[C:32](=[O:33])[N:13]3[C:14]([C:19]([O:21][CH2:22][C:23]4[CH:28]=[CH:27][C:26]([N+:29]([O-:31])=[O:30])=[CH:25][CH:24]=4)=[O:20])=[C:15](Br)[CH2:16][S:17][C@H:12]23)=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:34][NH:35][CH3:36]>>[C:1]1([CH2:7][C:8]([NH:10][CH:11]2[C:32](=[O:33])[N:13]3[C:14]([C:19]([O:21][CH2:22][C:23]4[CH:28]=[CH:27][C:26]([N+:29]([O-:31])=[O:30])=[CH:25][CH:24]=4)=[O:20])=[C:15]([N:35]([CH3:36])[CH3:34])[CH2:16][S:17][C@H:12]23)=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 674DimethylamineHCID 70632447HCID 70632447, compound

Product 1

HCID 70632488HCID 70632488, compound

Procedure

p-Nitrobenzyl 7-phenylacetamido-3-bromo-3-cephem-4-carboxylate is reacted with dimethylamine by following the reaction conditions of Example 4 to provide p-nitrobenzyl 7-phenylacetamido-3-dimethylamino-3-cephem-4-carboxylate.

Workup

  1. customthe reaction conditions of Example 4

Sources & evidence

ORD record
ord-f40a37911e474935bd361e4d226a18aa
Source dataset
uspto-grants-1977_03
Patent number
US04013651

Reaction notes

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