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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 597174Generated: October 30, 2026

1-Methyl-4-piperidone → 1,2,7,8,9,10-Hexahydro-8-methylpyrido[3',4':4,5]pyrrolo[1,2,3-de][1,4]benzoxazine hydrochloride

https://huagongshe.com/reaction/597174

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Methyl-4-piperidoneHCID 74049—
Reactant2H-benzo[b][1,4]oxazin-4(3H)-amine hydrochlorideHCID 22488985—
Product1,2,7,8,9,10-Hexahydro-8-methylpyrido[3',4':4,5]pyrrolo[1,2,3-de][1,4]benzoxazine hydrochlorideHCID 20304738—

Reaction Steps

By a procedure similar to Example 110, 4-amino-3,4-dihydro-2H-1,4-benzoxazine hydrochloride is reacted with 1-methyl-4-piperidone to yield the title compound, m.p. 245°-246° .

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04013652
Source datasetuspto-grants-1977_03
ORD IDord-c1de4c4ce1e744128e51b650cdd4b7be
Source noteuspto-grants-1977_03