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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 597219Generated: October 30, 2026

Benzoyl isothiocyanate → HCID 178523941, compound

https://huagongshe.com/reaction/597219

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzoyl isothiocyanateHCID 68284—
ReactantHCID 178511469HCID 178511469—
SolventChloroformHCID 6212—
ProductHCID 178523941HCID 17852394163.7%

Reaction Steps

(i) A solution of 2-(4-imidazolylmethylthio)ethylamine (6.0 g) and benzoyl isothiocyanate (6.0 g) in chloroform (150 ml) was heated under reflux for one hour. Concentration followed by recrystallisation from ethyl acetate-isopropyl acetate afforded N-benzoyl-N'-(2-(4-imidazolylmethylthio)-ethyl)thiourea (7.5 g). An analytically pure sample (from aqueous isopropyl alcohol) had m.p. 126°-128°.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04013659
Source datasetuspto-grants-1977_03
ORD IDord-6bbef1235d7d4d1283a395f2a10a5656
Source noteuspto-grants-1977_03