HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,2,2-Trifluoroethyl 2,5-bis(2,2,2-trifluoroethoxy)benzoate → N-[1-(Piperidin-2-yl)ethyl]-2,5-bis(2,2,2-trifluoroethoxy)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,2,2-Trifluoroethyl 2,5-bis(2,2,2-trifluoroethoxy)benzoate | HCID 11281014 | — |
| Reactant | (1-Piperidin-2-ylethyl)amine | HCID 21890255 | — |
| Product | N-[1-(Piperidin-2-yl)ethyl]-2,5-bis(2,2,2-trifluoroethoxy)benzamide | HCID 21447146 | — |
Reaction Steps
Starting with 2,2,2-trifluoroethyl 2,5-bis(2,2,2-trifluoroethoxy)benzoate and 2-(1-aminoethyl)piperidine and using the procedure illustrated in Examples 21 and 22, the product 2,5-bis(2,2,2-trifluoroethoxy)-N-[1-(2-piperidyl)ethyl]-benzamide, m.p. 95°-97° C., is obtained as white needles.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04013670 |
| Source dataset | uspto-grants-1977_03 |
| ORD ID | ord-dd72badaf4734cb0ae53f147f94f4c90 |
| Source note | uspto-grants-1977_03 |