HuagongsheHuagongshe Chemistry Print Report · For research reference only
8,9-dimethoxy-1,2,3,4-tetrahydro-5H-chromeno[3,4-c]pyridin-5-one → 1,2,3,4-Tetrahydro-8,9-dimethoxy-3-(1-methyl-2-morpholinoethyl)-5H-[1]benzopyrano[3,4-c]pyridin-5-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 8,9-dimethoxy-1,2,3,4-tetrahydro-5H-chromeno[3,4-c]pyridin-5-one | HCID 10825289 | — |
| Reactant | 4-(2-Chloropropyl)morpholine | HCID 15104445 | — |
| Product | 1,2,3,4-Tetrahydro-8,9-dimethoxy-3-(1-methyl-2-morpholinoethyl)-5H-[1]benzopyrano[3,4-c]pyridin-5-one | HCID 21447170 | — |
Reaction Steps
In the same way described in Example 5, 0.02 m of 1,2,3,4-tetrahydro-8,9-dimethoxy-5H-[1]benzopyrano[3,4-c]pyridin-5-one was alkylated with N-(2-chloropropyl)-morpholine to give, after recrystallization from 95% EtOH 1.3 g of product; mp 228°-230° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04013671 |
| Source dataset | uspto-grants-1977_03 |
| ORD ID | ord-667c7ade0c0e45ad918853e4541ec827 |
| Source note | uspto-grants-1977_03 |