Acetyl chloride → HCID 21447338, compound

Participants

Reaction Steps

20 g of 3-cyclohexyl anisole are dissolved in 200 cc of benzene, 8.15 g of acetyl chloride are added, and 27.4 g of tin(IV) chloride are subsequently added dropwise at 5° - 10° while stirring. After stirring at 23° for 16 hours, the reaction mixture is poured on ice and extracted thrice with benzene. The organic phase is successively washed with 2 N hydrochloric acid, a 2 N caustic soda solution and water, is dried over anhydrous sodium sulphate and concentrated. The residue is recrystallized from acetone/petroleum ether. The resulting title compound has a M.P. of 99°-100°.

Provenance & Evidence