Water → HCID 21447330, compound

Participants

Reaction Steps

2 g of 2-(3-cyclohexyl-phenoxy)propionic acid in 180 cc of 95% ethanol are irradiated with a 150 Watt mercury high pressure burner for 2 hours in an atmosphere of argon and while cooling with water. The solution is concentrated by evaporation and the residue is chromatographed on 150 g of silica gel. By-products are first eluted with ethyl acetate/hexane (1:1). Elution with ethyl acetate finally yields pure 2-(4-cyclohexyl-2-hydroxyphenyl)propionic acid.

Provenance & Evidence