HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-Amino-3-methoxymethyl-3-cephem-4-carboxylic acid → 7-Trifluoroethylmercaptoacetamido-3-methoxymethyl-3-cephem-4-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-Amino-3-methoxymethyl-3-cephem-4-carboxylic acid | HCID 12833023 | — |
| Reactant | [(2,2,2-Trifluoroethyl)sulfanyl]acetyl chloride | HCID 21816785 | — |
| Product | 7-Trifluoroethylmercaptoacetamido-3-methoxymethyl-3-cephem-4-carboxylic acid | HCID 131710235 | — |
Reaction Steps
Using the procedure of Example 1, 7-amino-3-methoxymethyl-3-cephem-4-carboxylic acid is acylated with trifluoroethylmercaptoacetyl chloride to give 7-trifluoroethylmercaptoacetamido-3-methoxymethyl-3-cephem-4-carboxylic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04013765 |
| Source dataset | uspto-grants-1977_03 |
| ORD ID | ord-1296105fbc444f9d85dc4257cfb90d11 |
| Source note | uspto-grants-1977_03 |