Veratraldehyde → 5-[(3,4-Dimethoxyphenyl)methylidene]imidazolidine-2,4-dione

Participants

Reaction Steps

It was previously reported by Deulofeu and Mendivelzua, Z. physiol, Chem. 219, 233 (1933) that the condensation of veratraldehyde (3,4-dimethoxybenzaldehyde) with hydantoin in acetic anhydride in the presence of fused anhydrous sodium acetate gave 5-(3',4'-dimethoxybenzal) hydantoin. We have now found, however, that this reaction leads to the formation of a corresponding acetylated product.

Provenance & Evidence